The water-soluble extract, organic extract component, and their combination resulted in similar change of the microbiota composition. (A) Bacterial beta diversity for comparing each group. PCoA plots of unweighted UniFrac distance metrics obtained from sequencing the 16S rDNA in feces. (Cellulose (n = 6), Jerusalem artichoke (n = 6), water-soluble extract (n = 6), organic extract (n = 6), insoluble extract (n = 6), water-soluble extract + organic extract (n = 6), water-soluble extract + insoluble extract (n = 6)). (B) The average of unweighted UniFrac distance between groups. The number in (B) indicates the average distance calculated by UniFrac distance metrics. Cellulose, Jerusalem artichoke, water-soluble extract, organic extract, or insoluble extract are Cont., A, B’, D, or E, respectively.