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. 2020 May 16;7(2):44. doi: 10.3390/bioengineering7020044

Figure 3.

Figure 3

Potent and selective antagonists of Nav1.7 and Nav1.8 inhibit thermally evoked responses in sensitized adult DRG cultures. (A) Raster plots of three representative electrodes at 37 °C (left), 45 °C (middle), and after the addition of 30 nM HWTX-IV. (B) Raster plots of three representative electrodes at 37 °C, 45 °C, and after the addition of 300 nM A-803467. Summarized percentage of temperature responsive electrodes at baseline and after the addition of (C) Nav1.7 blocker (30 nM HWTX-IV) and (D) Nav1.8 blocker (300 nM A-803467).