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. 2020 May 16;7(2):44. doi: 10.3390/bioengineering7020044

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Nav1.7/1.8 expression is maintained in adult DRG neurons in vitro and is unchanged by treatment with IL-6 and NGF. (A) Representative immunofluorescence images of adult DRG neurons stained for Nav1.7 (top left; red), Nav1.8 (top right; green), and neuronal marker NeuN (bottom left; blue). (B) Percentage of Nav1.7, Nav1.8, and Nav1.7/1.8 co-expressing neurons following exposure to IL-6 and NGF for 72 hours or vehicle. (C) mRNA expression of Nav1.7 and Nav1.8 normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) following exposure to IL6 and NGF for 72 hours or vehicle. Errors are expressed as mean ± STD.