Table 2.
Polyphenol binding sites characterization.
| Molecular Target |
Catalytic Site |
Allosteric Site |
Residues Involved |
Ref. |
|---|---|---|---|---|
| Alpha-glucosidase | √ | R407, R197, R407, F282 | Jhong et al., 2015 [19] | |
| Alpha-Amylase | √ | K200, E233, D300, W151, A198, L162 | Jhong et al., 2015 [19] | |
| 3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCoAR) |
√ (NADP binding site) |
K691, E559, D767 | Islam et al., 2015 [20] | |
| Pancreatic Lipase | √ | F78, Y115, H152, F216 | Martinez Gonzales et al., 2017 [21] | |
| Angiotensin-converting enzyme (ACE) | √ | S1′, S2′/S1′, S2′ regions | Guerrero et al., 2012 [22] |