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Immunohistochemical analysis of COX-2 expression. Saline (A); 5-FU (B); RUT-200 (C); CLX (D); RUT and CLX (E). % immunolabelled for COX-2 (F). Values are expressed as mean ± SEM. For statistical analysis, one-way ANOVA was used, followed by Tukey’s test. # p < 0.05 vs. saline group, * p < 0.05 vs. group 5-FU.
