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. 2020 Jun 17;9(6):757. doi: 10.3390/plants9060757

Figure 1.

Figure 1

Anti-melanoma effect of methanol extracts obtained from Abeliophyllum distichum leaves (AL), fruit (AF), and branches (AB). (A) Effect of A. distichum organ extracts on the cell viability of SK-MEL-2 cells. SK-MEL-2 cells were treated with different concentrations of each extract for 48 h, and cell viability was determined using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. 10 μM of Quercetin was used as positive control. (B) Time and dose dependence of the anti-melanoma effect induced by AL. (C) Effect of AL on the cell viability of B16F10 murine melanoma cells and HDFa human dermal fibroblast cells. B16F10 cells and HDFa cells were treated with the indicated doses of AL for 48 h, and the viabilities of the cells were determined. The values are the means of three independent experiments, and the error bars represent the standard error. Values in the same column with different superscript letters are significantly different (p < 0.05).