| Disease | Advanced cancer/solid tumor only |
| Stage of Disease/Treatment | Metastatic/advanced |
| Prior Therapy | No designated number of regimens |
| Type of Study – 1 | Phase I |
| Type of Study – 2 | Dose evaluation |
| Primary Endpoint | Safety |
| Primary Endpoint | Tolerability |
| Secondary Endpoint | Clinical benefit per objective response or progression‐free survival (RECIST version 1.1) |
| Additional Details of Endpoints or Study Design | Exploratory endpoint: immune analysis |
| Investigator's Analysis | Drug tolerable, some efficacy observed in chordoma |