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. 2019 Dec 26;25(7):560–e1006. doi: 10.1634/theoncologist.2019-0932
Drug 1
Generic/Working Name MVA‐BN‐Brachyury
Company Name Bavarian Nordic
Drug Type Poxviral‐vector vaccine
Dose 8 × 108 IU given as four injections (1 injection = 2 × 108 IU)
Route Subcutaneous
Schedule of Administration Two doses were administered at monthly (28 ± 4 days) intervals for 2 months. Each dose consisted of four injections, one in each extremity.
Drug 2
Generic/Working Name FPV‐BN‐Brachyury
Company Name Bavarian Nordic
Drug Type Poxviral‐vector vaccine
Dose Single injection of 1 × 109 IU
Route Subcutaneous
Schedule of Administration The first dose of FPV‐BN‐Brachyury was administered beginning 1 month (28 days ± 4 days) after the second dose of MVA‐BN‐Brachyury. It was administered at monthly (28 days ± 4 days) intervals for six doses then every 12 weeks (−4 days up to +14 days) for a total treatment duration of 2 years.