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. 2020 Jun 17;9(6):1897. doi: 10.3390/jcm9061897

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Baseline and 12-month follow-up values of VE/VCO_2slope stratified by ARNI dose. Captions: angiotensin receptor neprilysin inhibitor (ARNI) dose (ARNI₁ = 24/26 mg bid, ARNI₂ = 49/51 mg bid, and ARNI₃ = 97/103 mg bid); the slope of increase in ventilation over carbon dioxide output (VE/VCO2slope); * p < 0.0001 (ANOVA).