Table 5.
Baseline and 12-month follow-up cardiopulmonary parameters in overall population.
| CPET Parameters | Baseline | 12-Month Follow-Up | p Value |
|---|---|---|---|
| VO2peak (mL/kg/min) | 15.3 ± 3.7 | 17.8 ± 4.2 | <0.0001 |
| Predicted VO2peak (%) | 56.4 ± 13.9 | 64.8 ± 17.8 | <0.0001 |
| Watt Max (W) | 72.8 ± 25.1 | 90.5 ± 28.1 | <0.0001 |
| VE/VCO2slope | 33.4 ± 6.2 | 30.3 ± 6.5 | <0.0001 |
| RER | 1.14 ± 0.12 | 1.14 ± 0.15 | 0.836 |
| HR Rest (bpm) | 72.4 ± 10.8 | 68.9 ± 12.1 | 0.329 |
| HR Peak (bpm) | 106.6 ± 18.2 | 110.9 ± 20.6 | 0.001 |
| HRR (bpm) | 11.4 ± 9.5 | 17.4 ± 15.1 | 0.004 |
| AT-VO2 (mL/kg/min) | 11.4 ± 2.9 | 12.1 ± 3.6 | 0.015 |
| AT-VO2 (%) | 40.9 ± 11.5 | 55.5 ± 84.6 | 0.173 |
| AT-Watt (W) | 56.1 ± 24.8 | 58.5 ± 22.1 | 0.536 |
| O2-Pulse (mL/beat) | 11.4 ± 3 | 13.7 ± 4.6 | <0.0001 |
| ΔVO2/Δwork (mL/min/watt) | 9.2 ± 1.6 | 10.2 ± 1.5 | <0.0001 |
| Peak Ventilation (L/min) | 48.1 ± 12.3 | 61.4 ± 18.9 | <0.0001 |
| TIDAL Volume (mL/kg) | 1.5 ± 0.38 | 2.2 ± 3.7 | 0.114 |
| Respiratory Rate (breaths/min) | 30.8 ± 6.3 | 33.6 ± 7.4 | <0.0001 |
Captions: AT: anaerobic threshold; RER: respiratory exchange ratio; VE: ventilation; VE/VCO2slope: the slope of increase in ventilation over carbon dioxide output; VO2: oxygen consumption; HR: heart rate; HRR: heart rate recovery; CPET: cardiopulmonary exercise stress testing.