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. 2020 Jun 18;10(6):923. doi: 10.3390/biom10060923

Table 5.

List of effective antimicrobial phenolic compounds derived from plants extracts.

Compound Mechanisms of Action Target References
p-Coumaric
Caffeic acid
Ferulic acid
Damaging the cytoplasmic membrane by inducing ion leakages and proton influx Oenococcus oeni and Lactobacillus hilgardii [135]
Myricetin Inhibition of the intrinsic efflux pump system Mycobacterium smegmatis [136]
Luteolin Inhibition of the intrinsic efflux pump system Mycobacteria spp. [136,137]
Naringenin
Eriodictyol
Taxifolin
Inhibition of β-Ketoacyl–Acyl Carrier Protein Synthase III (PfKASIII) Enterococcus faecalis [138]
Quercetin Inhibition of the intrinsic efflux pump system S. aureus [139]
Targeting d-Alanine:d-alanine Ligase Helicobacter pylori and E. coli [140]
Apigenin Targeting d-Alanine:d-alanine Ligase Helicobacter pylori and E. coli [140]
Kaempferol Inhibition of the intrinsic efflux pump system C. albicans and S. aureus [141,142]