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. 2020 May 11;25(7):e1051–e1059. doi: 10.1634/theoncologist.2020-0063

Table 1.

Patients with stage 1B2 cervical cancer who completed neoadjuvant chemotherapy followed by vaginal radical trachelectomy and pelvic lymph node dissection

Patient Age, yr Histology Grade Invasion depth, mm Tumor size, mm Lymph nodes LVSI Cycles of NACT Path response to NACT Recurrence Treatment recurrence DFS, months OS, months Current status
1 28 SCC 3 5 37 0/19 No 6/6 Partial No n/a 109.8 109.8 NED
2 30 SCC 1 6 25 0/12 Yes 5/6 Partial Yes Surgery + CRT 105.7 110.8 NED
3 24 SCC 3 5 35 0/19 Yes 4/6 Complete No n/a 103.5 103.5 NED
4 30 SCC 2 5 20 0/14 No 2/6 Partial No n/a 100.3 100.3 NED
5 29 SCC 3 5 35 0/23 No 6/6 Complete No n/a 51.4 51.4 NED
6 25 SCC 2 8 30 0/20 Yes 6/6 Complete No n/a 52.0 52.0 NED
7 36 AC 3 6 38 0/19 Yes 6/6 Partial Yes Surgery + CT + HPV16 vaccine 23.6 67.5 Palliative care
8 30 ASC 2 6 35 0/31 Yes 6/6 Partial yes CRT 18.1 32.7 NED
9 29 AC 2 15 28 0/43 No 6/6 Partial No n/a 48.1 48.1 NED
10 31 SCC 3 5 20 0/16 Yes 6/6 Complete No n/a 12.4 12.4 NED
11 23 SCC 3 4 20 0/18 Yes 6/6 Complete No n/a 37.1 37.1 NED
12 25 SCC 2 5 36 0/28 No 6/6 Complete No n/a 29.2 29.2 NED
13 31 AC 1 7 35 0/19 No 6/6 Partial No n/a 19.3 19.3 NED
14 30 SCC 3 6 40 0/11 Yes 6/6 Partial No n/a 11.4 11.4 NED

All patients had stage IB2 and received cisplatin/carboplatin and paclitaxel (70 mg/m2) as NACT.

Abbreviations: AC, adenocarcinoma; ASC, adenosquamous carcinoma; CRT, chemoradiation; CT, chemotherapy; DFS, disease‐free survival; HPV16, human papillomavirus 16; LVSI, lymph vascular space invasion; n/a, not applicable; NACT, neoadjuvant chemotherapy; NED, no evidence of disease; OS, overall survival; Path response to NACT, pathological response after surgery; SCC, squamous cell carcinoma.