Table 1.
Patient | Age, yr | Histology | Grade | Invasion depth, mm | Tumor size, mm | Lymph nodes | LVSI | Cycles of NACT | Path response to NACT | Recurrence | Treatment recurrence | DFS, months | OS, months | Current status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 28 | SCC | 3 | 5 | 37 | 0/19 | No | 6/6 | Partial | No | n/a | 109.8 | 109.8 | NED |
2 | 30 | SCC | 1 | 6 | 25 | 0/12 | Yes | 5/6 | Partial | Yes | Surgery + CRT | 105.7 | 110.8 | NED |
3 | 24 | SCC | 3 | 5 | 35 | 0/19 | Yes | 4/6 | Complete | No | n/a | 103.5 | 103.5 | NED |
4 | 30 | SCC | 2 | 5 | 20 | 0/14 | No | 2/6 | Partial | No | n/a | 100.3 | 100.3 | NED |
5 | 29 | SCC | 3 | 5 | 35 | 0/23 | No | 6/6 | Complete | No | n/a | 51.4 | 51.4 | NED |
6 | 25 | SCC | 2 | 8 | 30 | 0/20 | Yes | 6/6 | Complete | No | n/a | 52.0 | 52.0 | NED |
7 | 36 | AC | 3 | 6 | 38 | 0/19 | Yes | 6/6 | Partial | Yes | Surgery + CT + HPV16 vaccine | 23.6 | 67.5 | Palliative care |
8 | 30 | ASC | 2 | 6 | 35 | 0/31 | Yes | 6/6 | Partial | yes | CRT | 18.1 | 32.7 | NED |
9 | 29 | AC | 2 | 15 | 28 | 0/43 | No | 6/6 | Partial | No | n/a | 48.1 | 48.1 | NED |
10 | 31 | SCC | 3 | 5 | 20 | 0/16 | Yes | 6/6 | Complete | No | n/a | 12.4 | 12.4 | NED |
11 | 23 | SCC | 3 | 4 | 20 | 0/18 | Yes | 6/6 | Complete | No | n/a | 37.1 | 37.1 | NED |
12 | 25 | SCC | 2 | 5 | 36 | 0/28 | No | 6/6 | Complete | No | n/a | 29.2 | 29.2 | NED |
13 | 31 | AC | 1 | 7 | 35 | 0/19 | No | 6/6 | Partial | No | n/a | 19.3 | 19.3 | NED |
14 | 30 | SCC | 3 | 6 | 40 | 0/11 | Yes | 6/6 | Partial | No | n/a | 11.4 | 11.4 | NED |
All patients had stage IB2 and received cisplatin/carboplatin and paclitaxel (70 mg/m2) as NACT.
Abbreviations: AC, adenocarcinoma; ASC, adenosquamous carcinoma; CRT, chemoradiation; CT, chemotherapy; DFS, disease‐free survival; HPV16, human papillomavirus 16; LVSI, lymph vascular space invasion; n/a, not applicable; NACT, neoadjuvant chemotherapy; NED, no evidence of disease; OS, overall survival; Path response to NACT, pathological response after surgery; SCC, squamous cell carcinoma.