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Fluorescent confocal microscopy images of live HeLa cells exposed to rhodamine B isothiocyanate (RBITC)-labelled mesoporous silica particles (MSP). Cell were stained with acridine orange (AO, green channel) and a specific marker for lysosomes (Lysotracker®, blue channel). All intracellular MSP were contained inside lysosomes (purple arrow). Empty lysosomes are labelled in blue (blue arrow). Free cytosolic particles (only red fluorescence) were not detected.
