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. 2020 May 26;9(6):1616. doi: 10.3390/jcm9061616

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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High resolution Ultrasound, multi-frequency C1-6 MHz probe, direct comparison of B-mode (A), microbubble enhanced ultrasound (MEU) (B), and hybrid mode (C) 90 minutes after liposomal vitamin C uptake. (A) B-mode after application of the microbubbles with vitamin C (B): enhanced signal in the subtraction image with low MI ≤ 0.16, high signal intraluminal in the stomach-duodenum, mesenteric vessels, and liver corresponding to the enhancement of the MEU. (C) Visualization of the microbubbles with the hybrid subtraction mode. Clear enhancement of the bubbles in the intraluminal vessels, stomach/duodenum, and liver.