Table 3.
Annual rate of weight change pre and post switch to integrase strand transfer inhibitors (INSTI), according to INSTI regimen. For the non-INSTI group the date of the switch (T0) was randomly assigned, assuming that the weight change was constant over the study period.
| Weight Change in kg/Year | Non-INSTI Group * (N = 21) |
INSTI Group * (N = 45) |
|---|---|---|
|
Pre-T0
(p-value) |
+0.38 (−0.21–0.97) (0.204) |
+0.51 (0.11–0.91) (0.014) |
|
Post- T0
(p-value) |
+0.74 (0.15–1.34) (<.0001) |
+0.79 (0.38–1.19) (0.0002) |
|
Pre-post Difference
(p-value) |
+0.36 (−0.47–1.20) (0.391) |
+0.28 (−0.29–0.85) (0.338) |
* Adjusted for age, sex and weight at baseline.