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. 2020 Jun 26;25(12):2953. doi: 10.3390/molecules25122953

Figure 1.

Figure 1

BML-111 reduces neutrophil recruitment in a dose-dependent manner and in an ALX/FPR2-sensitive manner. The effect of BML-111 in MPO activity was determined in samples dissected 12 h after the radiation (A–C). (A) Dose–response curve to determine the effect of BML-111. (B) Time–response curve to evaluate whether BML-111 presents a time-dependent effect. (C) Dose–response curve for BOC, an ALX/FPR2 antagonist. Results are expressed as mean ± SEM and are representative of two independent experiments. One-way ANOVA followed by Tukey’s post-test * p < 0.05 compared to non-irradiated group, # p < 0.05 compared to irradiated vehicle-treated group, ## p < 0.05 compared to BML-111 group.