Figure 2.
BML-111 reduces skin edema and the increase in epidermal thickness induced by UVB radiation. The skin edema (A) were determined in samples dissected 12 h after the radiation. The epidermal thickness was determined in samples dissected 12 h after the radiation and stained with hematoxylin and eosin (H&E). Representative images of non-irradiated control (B), irradiated treated with vehicle (C), irradiated treated with 0.1 mg/kg of BML-111 (D), irradiated treated with BOC and BML-111 (E), and irradiated treated with BOC (F) groups are presented. Epidermal thickness of experimental groups is presented in μm (G). Original magnification 40×; 100 μm. Results are expressed as mean ± SEM and are representative of two independent experiments. One-way ANOVA followed by Tukey’s post-test * p < 0.05 compared to non-irradiated group, # p < 0.05 compared to irradiated vehicle-treated group, ## p < 0.05 compared to BML-111 group.
