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. 2020 Jun 2;9(6):1689. doi: 10.3390/jcm9061689

Table 8.

Summary of studies examining psychological factor–QoL (n = 14).

Author (Year) Cohort Exercise Intervention Duration Outcome Measures Results
[11] Mereles et al. (2006) human (n = 30) combined training + RMT 15 weeks SF-36 ↑ QoL in physical (p = 0.013) and mental (p = 0.027) component
[76] Shoemaker et al. (2009) human (n = 2) cycling 6 weeks CRQ
CAMPHOR
↑ QoL in both subjects (no SS)
↑ QoL in one subject (no SS)
[91] Martínez-Quintana et al. (2010) human (n = 8) combined training 12 weeks SF-12 No improvement in QoL
[37] Grünig et al. (2011) human (n = 58) combined training + RMT 15 weeks SF-36 ↑ QoL (p < 0.05)
[53] Ganderton et al. (2011) human (n = 19) combined training 2 × 12 weeks SF-36
CAMPHOR
No SS in improved QoL
No SS in improved QoL
[12] Grünig et al. (2012a) human (n = 183) combined training + RMT 15 weeks SF-36 ↑ QoL (p < 0.05)
[93] Grünig et al. (2012b) human (n = 21) combined training + RMT 15 weeks SF-36 ↑ QoL in physical functioning
(p = 0.025), general health perception (p = 0.049), social functioning (p = 0.008), mental health (p = 0.033) and vitality (p = 0.021)
[36] Becker-Grünig et al. (2013) human (n = 20) combined training + RMT 15 weeks SF-36 No SS in improved QoL
↑ in bodily pain score (p = 0.05)
[69] Chan et al. (2013) human (n = 23) running 10 weeks SF-36

CAMPHOR
↑ QoL in ET (group × time effect) (p < 0.05)
↑ QoL in ET (group × time effect) (p < 0.05)
[96] Ehlken et al. (2016) human (n = 87) combined training + RMT 15 weeks SF-36 No SS in improved QoL
↑ in ET group vitality score (p = 0.036)
[97] Bussotti et al. (2017) human (n = 15) combined training + RMT 4 weeks HADS
EQ-5D
↓ anxiety and depression (p < 0.01)
↑ QoL (p < 0.01)
[73] Gerhardt et al. (2017) human (n = 22) WBV 4 weeks SF-36

LPH
↑ QoL in ET (group × time effect)
↑ QoL (p < 0.001)
↓ LPH total score (p < 0.001)
[98] González-Saiz et al. (2017) human (n = 40) combined training + RMT 8 weeks SF-36 ↑ QoL in mental component (No SS)
↑ QoL in physical component (time effect) (p = 0.002)
[77] Brown et al. (2018) human (n = 11) walking 12 weeks SF-36 ↑ QoL in physical component (p = 0.02)
↑ in physical functioning (p = 0.03) and energy/fatigue score(p = 0.02)

CAMPHOR, Cambridge Pulmonary Hypertension Outcome Review; RQ, Chronic Respiratory Disease Questionnaire; ET, exercise training; LPH, living with pulmonary hypertension questionnaire; QoL, quality of life; RMT, respiratory muscle training; SF-36, Short Form 36; SS, statistical significance; WBV, whole-body vibration.