Figure 11.

Cumulative concentration-response curves of spasmolytic activity of Thymus vulgaris L. free EO, SEO, and excipients and otilonium bromide (OB) against potassium chloride- (80 mM) induced contraction on guinea pig ileum (panels A and B) and colon (panels C and D). Each point is the mean ± SEM of four-six experiments. Where error bars are not shown these are covered by the point itself. For a better comparison of the effects, numbers in brackets represent the effective EO concentration (mg/mL) in SEO (panels A and C) or the amount of OB present in 1 mL (panels B and D).