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. 2020 Jun 22;25(12):2869. doi: 10.3390/molecules25122869

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of fucoidans on immunoglobulin levels in the serum. Levels of (A) total IgE, (B) OVA-specific IgE, (C) OVA-specific IgG1, and (D) OVA-specific IgG2a in serum. Values are expressed as means ± SEM (n = 3). * (p < 0.05), *** (p < 0.0005) represent significant increases compared with the healthy control, and † (p < 0.05), †† (p < 0.005) represent significant decreases compared with the OVA + PM group. # (p < 0.05) represents a significant increase compared with the OVA only group. N.D; not detected.