. 2020 Jun 22;8(6):938. doi: 10.3390/microorganisms8060938

Table 3.

Linear regression models constructed with BMI as dependent variable, relative abundance of Prevotellaceae family, and genetic risk score (GRS) as independent variables.

Model	Whole Population (n = 360)			Men (n = 109)			Women (n = 251)
Model	β ± SE	p Value	adjR²	β ± SE	p Value	adjR²	β ± SE	p Value	adjR²
Model A		<0.001	0.18		0.007	0.11		<0.001	0.21
Prevotellaceae	−0.27 ± 0.25	0.276		0.004 ± 0.38	0.992		−0.44 ± 0.31	0.164
GRS	0.07 ± 0.50	0.887		0.70 ± 0.80	0.383		−0.23 ± 0.63	0.713
Prevotellaceae#GRS	0.06 ± 0.04	0.098		−0.006 ± 0.06	0.925		0.10 ± 0.05	0.039
Model B		<0.001	0.18		0.003	0.13		<0.001	0.19
Leuconostocaceae	−1.37 ± 1.02	0.179		−2.12 ± 1.75	0.228		−0.17 ± 1.38	0.903
GRS	0.76 ± 0.16	<0.001		0.51 ± 0.26	0.053		0.96 ± 0.21	<0.001
Leuconostocaceae#GRS	0.23 ± 0.15	0.121		0.29 ± 0.28	0.305		0.08 ± 0.19	0.657
Model C		<0.001	0.17		0.17	0.003		<0.001	0.19
Lactobacillaceae	0.42 ± 0.35	0.231		0.48 ± 0.48	0.316		0.42 ± 0.48	0.382
GRS	0.99 ± 0.24	<0.001		0.79 ± 0.36	0.032		1.15 ± 0.31	<0.001
Lactobacillaceae#GRS	−0.03 ± 0.05	0.506		−0.05 ± 0.07	0.511		−0.03 ± 0.07	0.648

β represents changes in outcomes for the increasing number of units of BMI in the whole population and separating by sex; SE: standard error. Regression was adjusted for age, sex, physical exercise and energy intake excepting models stratified by sex in which the gender was not considered.