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. 2020 Jun 17;25(12):2805. doi: 10.3390/molecules25122805

Table 2.

MtbTMPK inhibitory activity of the compounds.

graphic file with name molecules-25-02805-i012.jpg

Compound R IC50 (μM) a Compound R IC50 (μM)
3 graphic file with name molecules-25-02805-i013.jpg 17 ± 2 21k graphic file with name molecules-25-02805-i014.jpg 126 ± 10
21f graphic file with name molecules-25-02805-i015.jpg 49 ± 7 21l graphic file with name molecules-25-02805-i016.jpg 91 ± 10
21g graphic file with name molecules-25-02805-i017.jpg 45 ± 2 21m graphic file with name molecules-25-02805-i018.jpg 135 ± 22
21h graphic file with name molecules-25-02805-i019.jpg 49 ± 8 21o graphic file with name molecules-25-02805-i020.jpg 70 ± 9
21i graphic file with name molecules-25-02805-i021.jpg 34 ± 5 21p graphic file with name molecules-25-02805-i022.jpg ND b
21j graphic file with name molecules-25-02805-i023.jpg 5.0 ± 0.7 21q graphic file with name molecules-25-02805-i024.jpg 44 ± 2

a Values for which standard deviations are given are the calculated mean values of at least two measurements. b Solubility issue.