Figure 1.

Gastrointestinal pathogen loads following NAP treatment of C. jejuni infected secondary abiotic IL10^−/− mice. On day (d) 0 and d1 secondary abiotic IL10^-/- mice were perorally infected with C. jejuni strain 81-176 by gavage and treated intraperitoneally with either synthetic NAP (open circles) or placebo (PLC; closed circles) from d2 until d5. Upon necropsy on day 6 post-infection, luminal bacterial loads were quantitatively assessed in distinct gastrointestinal compartments by culture (in colony forming units per g; CFU/g) as indicated. Medians (black bars) and numbers of analyzed animals (in parentheses) are given. Data were pooled from four independent experiments.