Figure 3.

Graphical summary of the immune infiltration data in hereditary and sporadic MSI tumors. Studies that were assessed quantitatively were divided into three groups: studies reporting significantly higher immune infiltration counts in LS-associated MSI tumors compared to sporadic MSI tumors (“significantly higher in LS”), studies finding no significant differences between hereditary and sporadic MSI tumors (“no significant difference”) and studies reporting significantly higher immune infiltration counts in sporadic MSI tumors (“significantly higher in sporadic MSI”). Study size is proportional to the box area, and color indicates the respective marker. † study only counted immune cells in stromal regions. ‡ data for colorectal adenomas. * studies that analyzed MSI ECs.