Table 2.

The Gene Ontology (GO)_biological process (BP) terms enriched for the nodes in module A, B, C, and D (top 5 listed).

Module	ID	Name	Count	p value	Genes
Module A	GO:0000209	Protein polyubiquitination	8	5.44E − 11	MKRN1, FBXW7, TRIM36, HECTD2, UBE3C, UBE2B, FBXW11, UNKL
	GO:0016567	Protein ubiquitination	8	5.81E − 09	FBXW7, FBXO40, KBTBD8, FBXL5, ASB1, UBE2B, FBXW11, KLHL2
	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	3	1.76E − 04	FBXW7, FBXL5, FBXW11
	GO:0042787	Protein ubiquitination involved in ubiquitin-dependent protein catabolic process	3	6.99E − 03	HECTD2, UBE3C, TCEB1
	GO:0070936	Protein K48-linked ubiquitination	2	3.85E − 02	UBE2Q2, UBE2B
Module B	GO:0006954	Inflammatory response	5	2.94E − 05	S1PR3, AGTR2, HRH4, CXCL6, F2R
	GO:0007186	G-protein coupled receptor signaling pathway	5	8.28E − 04	S1PR3, AGTR2, GPR132, CXCL6, F2R
	GO:0032651	Regulation of interleukin-1 beta production	2	1.61E − 03	S1PR3, F2R
	GO:0030168	Platelet activation	3	1.62E − 03	F2RL2, PIK3R1, F2R
	GO:0007204	Positive regulation of cytosolic calcium ion concentration	3	2.19E − 03	S1PR3, HRH4, F2R
Module C	GO:0043550	Regulation of lipid kinase activity	3	3.90E − 06	RBL2, RBL1, RB1
	GO:0000082	G1/S transition of mitotic cell cycle	4	3.47E − 05	CDKN1A, CDK6, PPP3CA, RB1
	GO:0051726	Regulation of cell cycle	4	6.21E − 05	E2F5, RBL2, RBL1, RB1
	GO:0006470	Protein dephosphorylation	4	6.51E − 05	PPP2R3A, PPP3R1, PPP3CA, PPP2R2A
	GO:0010629	Negative regulation of gene expression	4	8.36E − 05	CDKN1A, RBL2, RBL1, RB1
Module D	GO:0042147	Retrograde transport, endosome to Golgi	3	8.94E − 04	STX16, VPS53, GCC2
	GO:0090161	Golgi ribbon formation	2	7.18E − 03	STX16, GCC2
	GO:0000042	Protein targeting to Golgi	2	1.30E − 02	GOLGA1, GCC2