Table 1.

Proposed paradigm shift from disease-based treatment to personalized activity self-management for osteoarthritis.

Current Best-Evidence: Disease-Based Treatment	Personalized Activity Self-Management
Disease-based, biomedically focussed eduation	Biopsychosocial education
Exercises target muscle strength, endurance, motor control, etc.	Physical activities targeting self-defined functional and/or social activities and life goals
Pain = sign of tissue damage, including inflammation	Pain = sign of nervous system sensitivity
Pain contingent approach to grading exercises	Operant conditioning and time contingent approach to grading daily activities