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Factors and responses of D-optimal mixture design.
| Factors | Low Limit (w/w%) | High Limit (w/w%) |
|---|---|---|
| X1: Capryol 90 | 10 | 30 |
| X2: Cremophor EL | 10 | 80 |
| X3: Tetraglycol | 10 | 80 |
| Responses | Goal | |
| Y1: Solubility (mg/g) | Maximize | |
| Y2: Precipitation (%) | Minimize | |
| Y3: Droplet size (nm) | Minimize | |
| Y4: Transmittance (%) | Maximize | |
