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. 2020 Jun 5;10(6):864. doi: 10.3390/biom10060864

Figure 1.

Figure 1

Screening S. venezuelae strains harboring chloramphenicol biosynthetic gene cluster (BGC). (A) Biosynthetic pathway of chloramphenicol. The three selected genes for PCR are colored as red. PAPA, L-p-aminophenylalanine; NRPS, non-ribosomal peptide synthetase; NH2-CAM, D-threo-1-(4-aminophenyl)-2-dichloroacetylamino-1,3-propanediol. (B) Organization of chloramphenicol BGC and detection of the three genes from the three S. venezuelae strains (ATCC 10712, ATCC 10595, and ATCC 21113). The three selected genes for PCR are colored navy. (C) Chloramphenicol production of the three S. venezuelae strains. N.D., Not detected. An asterisk indicates p-value < 0.05 (Wilcoxon rank-sum test).