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Indices for autoimmune abnormality and tear volume in mice. (a) The ratio of spleen weight-to-body weight. (b) The serum levels of anti-double stranded DNA (dsDNA) antibody. (c) Tear volume. BXSB: BXSB/MpJ. BXSB-Yaa: BXSB/MpJ-Yaa. Each bar represents the mean ± SE (n = 4). *Significant strain difference at the same age, Mann–Whitney U test. †Significant difference from the other groups, Kruskal–Wallis test followed by Scheffe’s method.
