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. 2020 May 21;245(12):999–1008. doi: 10.1177/1535370220928275

Figure 6.

Figure 6.

Histopathology of cornea in mice. (a) Cornea histology. The cornea is composed of four layers: the anterior epithelium (AE), the proper substance (PS), Descemet’s membrane (DM), and the posterior epithelium (PE). The anterior epithelia of the cornea thickened with age in BXSB, but not in BXSB-Yaa. HE staining. Bars (black) = 100 µm. Bars (inset) = 20 µm. (b) Thickness of corneal AE. (c) Scanning electron microscopy images of the anterior surface of the cornea. Numerous microvilli cover the surface of the cornea in BXSB, and they disappear in some areas in BXSB-Yaa at 28 weeks of age. The area without microvilli is surrounded by a dotted line. Bars = 5 µm. BXSB: BXSB/MpJ. BXSB-Yaa: BXSB/MpJ-Yaa Each bar represents the mean ± SE (n = 4). *Significant strain difference at the same age, Mann–Whitney U test. †Significant difference from the other groups, Kruskal–Wallis test followed by the Scheffe’s method. (A color version of this figure is available in the online journal.)