Figure 4.
Comparison of monomeric and dimeric structures of the same riboswitches. (a) Glycine aptamer 2 crystallized in a dimer (PDB 3OWI) configuration similar to the tandem glycine aptamer1-aptamer2 (PDB 3P49). (b) ZTP riboswitch dimer structure (PDB 4XWF) juxtaposed with its monomeric version (PDB 5BTP). (c) THF riboswitch crystallized in dimeric (PDB 3SUY and 3SUX) and monomeric version (PDB 4LVV). Ligands are shown in stick representation and semi-transparent red spheres. Interface regions are boxed and detailed on the right of each dimeric structure. Hydrogen bonding interactions are shown as magenta dashed lines, and stacking interactions are shown as solid magenta lines.