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. 2020 Apr 10;176(1):236–252. doi: 10.1093/toxsci/kfaa048

Table1.

Summary of Habits and Practices Data and Applied Dose Estimates for Face Cream and Body Lotion for the European Consumer

Product Types Face Cream Body Lotion
Amount of product used per day (g/day) using 90th percentilea 1.54 7.82
Frequency of useb 2 times/dayc 2 times/dayd
Amount of product in contact with skin per occasion (mg) 770 3910
Ingredient inclusion level 0.1% 0.1%
Skin surface area (cm2)b 565 15670e
Leave on or rinse off Leave on Leave on
Exposure duration per occasion 12 h 12 h
Amount of ingredient in contact with skin per occasion (mg)f 0.77 3.91
a

Hall et al. (2007).

c

Rounded from 2.14 times/day.

d

Rounded from 2.28 times/day.

e

Specified as Leg region in GastroPlus.

f

Based on 100% skin penetration and a body weight of 66.7 kg.

Source: Adapted from Moxon et al. (2020).