Table 1. MICs^a of Analogues for Alanine-Scanning.

		MRSAb				SAc	SFd	Enterococcus
no.	amino acid replaced	SA11	SA14	SA86	SA88	ATCC29213	SF	ET6	ET60	ATCC29212
	daptomycin	0.5	0.5	0.5	0.25	0.25	4	2	2	4
1	Trp1	≥32	≥32	≥32	≥32	≥32	≥64	≥64	≥64	≥64
2	d-Asn2	≥32	≥32	≥32	16	≥32	16	64	32	64
3	Asp3	≥32	≥32	16	16	16	≥32	≥32	≥32	≥32
4	Orn6	0.5	0.25	0.5	1	0.5	4	2	1	4
5	Asp7	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64
6	d-Ala8e	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64
7	Asp9	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64
8	3-mGlu12	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64	≥64
9	Kyn13	≥32	≥32	≥32	≥32	≥32	≥32	≥32	≥32	≥32

^aUnits in μg/mL.

^bMethicillin-resistant S. aureus.

^cS. aureus.

^dStreptococcus faecalis.

^eReplaced with l-Ala.