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. 2020 Jun 3;11(7):1442–1449. doi: 10.1021/acsmedchemlett.0c00175

Table 3. MICsa of Analogues with Side-Chain Amine of Different Lengths at Position 6.

graphic file with name ml0c00175_0005.jpg

    MRSAb
SAc SFd Enterococcus
no. modification SA11 SA14 SA86 SA88 ATCC29213 SF ET6 ET60 ATCC29212
  Orn 0.5 0.5 0.5 0.25 0.25 4 2 2 4
29 Dap 8 1 1 0.5 1 NDe ≥32 8 ≥32
30 Dab 2 0.5 0.25 0.25 0.25 NDe 16 8 16
17 Lys 16 ≥32 1 1 1 8 ≥32 16 ≥32
a

Units in μg/mL.

b

Methicillin-resistant S. aureus.

c

S. aureus.

d

Streptococcus faecalis.

e

Not determined.