Table 2. Results of the van’t Hoff Analysis of SPR Data.
| progenitor 18 | macrocycle 19 | |
|---|---|---|
| ΔG25°C (kJ mol–1) | –37.3 | –48.8 |
| ΔH (kJ mol–1) | –58.9 | –0.7 |
| ΔS (J K–1 mol–1) | –72.5 | 159.9 |
| pKd 25 °C | 6.6 | 8.4 |
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