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. 2020 Jun 19;11(7):1470–1475. doi: 10.1021/acsmedchemlett.0c00285

Table 1. NOS Inhibition% Given by Compounds 26, 9, 10, 17, 18, 23, and 24.

  %inhibition @ 1 μMa
% inhibition @ 10 μMa
Cpd iNOS nNOS eNOSa
2 81 ± 0.35 47 ± 0.23 3 ± 0.01
3 85 ± 0.58 10 ± 0.06 0 ± 0.01
4 93 ± 0.27 0 ± 0.07 5 ± 0.02
5 86 ± 0.25 14 ± 0.08 62 ± 0.21
6 70 ± 0.23 0 ± 0.03 4 ± 0.05
9 100 ± 0.55 2 ± 0.08 14 ± 0.12
10 100 ± 0.44 13 ± 0.24 4 ± 0.02
17 100 ± 0.76 0 ± 0.03 0 ± 0.01
18 87 ± 0.33 97 ± 0.21 0 ± 0.01
23 84 ± 0.24 96 ± 0.11 0 ± 0.01
24 100 ± 0.69 0 ± 0.01 0 ± 0.01
a

Values given are mean ± SD of experiments performed in triplicate.