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Cell Cytotoxicity of Paclitaxel and Rapamycin Individually and in Combination
| cell type | ES-2-luc human ovarian cancer | ES-2-luc ascites mouse ovarian cancer | ES-2-luc-PTXtreated ascites mouse ovarian cancer |
|---|---|---|---|
| IC50 of paclitaxel (nM) | 119.2 | 136.5 | 193.9 |
| IC50 of rapamycin (nM) | 647.8 | 549.0 | 482.9 |
| IC50 of paclitaxel/ rapamycin (nM) | 130.3 | 53.6 | 65.5 |
| combination index | 0.6473 | 0.2451 | 0.2368 |
