Fig. 2.

Change of cytokines and lymphocyte subsets in the same patients. a Line graphs showing the levels of IL-2R, IL-6, IL-8, and TNF-α for each fatal patient on admission and death (n = 42). One line represents one patient. ***P < 0.001 (Wilcoxon’s test). b Line graphs showing the numbers of B cells, CD4⁺ T cells, CD8⁺ T cells, and NK cells for each fatal patient on admission and death (n = 16). One line represents one patient. *P < 0.05, **P < 0.01, ***P < 0.001 (Wilcoxon’s test). c Line graphs showing the levels of IL-2R, IL-6, IL-8, and TNF-α for each survived patient on admission and discharge (n = 86). One line represents one patient. *P < 0.05, **P < 0.01, ***P < 0.001 (Wilcoxon’s test). d Line graphs showing the numbers of B cells, CD4⁺ T cells, CD8⁺ T cells, and NK cells for each survived patient on admission and discharge (n = 62). One line represents one patient. **P < 0.01, ***P < 0.001 (Wilcoxon’s test). IL-2, interleukin-2 receptor; IL-6, interleukin-6; IL-8, interleukin-8; TNF-α, tumor necrosis factor-α