Figure 7. Tinnitus severity correlates with VAChT puncta density changes in tinnitus animals.
Scatterplots of VAChT density (normalized to control) vs tinnitus index in the hilus of DG (A), stratum radiatum of CA3 (B), and in distal stratum radiatum of CA1 (C). Severity of tinnitus is indicated by increasing values of tinnitus index; each data point represents an individual animal. Shown in inset are Pearson Correlation Coefficients (r) and accompanying p value. VAChT density in all 3 areas correlate with tinnitus severity, though the association is stronger in synapse-rich layers of CA3 and CA1.