Figure 5. Manual percentage dystrophin-positive fiber (PDPF) analysis.
(A) Baseline values of PDPF for each patient are shown as open circles and part 2, week 48, intensity is shown as solid squares. This graphical representation provides a ready way to visualize relative changes in each patient. Data represent the mean of 3–4 replicates with SD bars. (B) Western blot protein change from baseline is plotted on the x-axis and percent dystrophin-positive fiber change from baseline as assessed by manual scoring is plotted on the y-axis. Spearman analysis shows a significant correlation (p < 0.001; r = 0.663). Each point represents a single patient.