Figure 2.

Molecular mechanisms for telomere lengthening in tumors. Number of samples with telomere lengthening had ATRX, TERT, or both or unknown mechanisms plotted for each subtype. Subtypes with fewer than five samples were pooled into one of the “other” groups. Note, one NBL patient (SJNBL044) had both ATRX alteration and TERT-expressing (depicted as a blue-colored bar). ACT = adrenocortical tumor; E2A = acute lymphoblastic leukemia B-lineage E2A-PBX1 subtype; HGG = high-grade glioma; NBL = neuroblastoma; OS = osteosarcoma.