Figure 5.

Longitudinal analyses of NK cell activated ADCC (antibody-specific- %CD107a⁺ cells [Log10]) in the plasma and GT (CVL) of women at 3 months, 6 months and 12 months, for the tenofovir and placebo arms for gp41. Analyses for cytotoxic activities (gp41-specific %CD107a⁺ cells [Log10]) in the plasma on the left (A) for gp41 and the genital tract on the right to (B) for gp41. Solid lines indicate the minimum and maximum values of box and whisker plots, with black solid lines across the dots indicate the median at each time point for each study arm. Wilcoxon signed-rank tests were done to determine statistical differences between NK cell activated ADCC activities within each arm of the study, for each protein. Statistically significant values were defined as p < 0.05. No adjustments were made for multiple comparisons.