Table 2. Cost-effectiveness of OPT compared to OPT plus ICD.
| Strategy | Costs (USD) | Incremental cost | QALY | Incremental QALY | ICER |
|---|---|---|---|---|---|
| Base-case | |||||
| OPT | 974 | 2.6056 | |||
| OPT + ICD | 10,992 | 10,018 | 3.3653 | 0.7596 | 13,187 |
| Sensitivity analysis - time horizon (5 and 20 years) | |||||
| OPT | 890 | 2.3859 | |||
| OPT + ICD | 10,322 | 9,432 | 2.8445 | 0.4585 | 20,569 |
| OPT | 987 | 2.6385 | |||
| OPT + ICD | 11,194 | 10,207 | 3.5225 | 0.8840 | 11,546 |
| Analysis by subgroups (ischemic and non-ischemic) | |||||
| OPT | 973 | 2.6029 | |||
| OPT + ICD | 11,314 | 10,341 | 3.5449 | 0.9420 | 10,977 |
| OPT | 1,243 | 3.3146 | |||
| OPT + ICD | 12,252 | 11,008 | 4.0488 | 0.7342 | 14,992 |
OPT: Optimal pharmaceutical therapy; ICD: Implantable cardioverter defibrillator; ICER: Incremental costeffectiveness ratio; QALY: Quality-adjusted life years