Table 1.
Demographical and Clinical Characteristics in Obese and Control Groups
| mean (SD) |
|||||
|---|---|---|---|---|---|
| control (n = 29) | case (n = 28) | P-valuea | confounderb | SOVc | |
| maternal age, years | 32.48 (5.66) | 32.10 (4.88) | 0.78 | yes | 0.79 |
| paternal age, years | 34.68(7.14) | 35.21(6.43) | 0.79 | yes | 0.94 |
| prepregnancy BMI, kg/m2 | 21.89(1.86) | 33.51(4.49) | 1.12 × 10−14 | yes | 1.61 |
| gestational age, weeks | 39.04(0.218) | 38.93(0.45) | 0.3812 | not included | |
| net weight gain | 30.85(10.92) | 29.4(13.55) | 0.7335 | ||
| baby weight (kg) | 3.29(0.32) | 3.54(0.5) | 0.03 | ||
| head circle (cm) | 34.89(1.10) | 35.55(1.36) | 0.05 | ||
| baby length (cm) | 51.3(1.9) | 51.4(2.36) | 0.8 | ||
| parity | 0.03 | yes | 0.80 | ||
| 0 | 5 | 2 | |||
| 1 | 16 | 7 | |||
| 2 | 7 | 10 | |||
| 3 and above | 1 | 9 | |||
| gravidity | 0.12 | yes | 0.98 | ||
| 1 | 5 | 1 | |||
| 2 | 12 | 5 | |||
| 3 | 7 | 8 | |||
| 4 and above | 5 | 14 | |||
| maternal ethnicity | 0.01 | yes | 0.73 | ||
| Caucasian | 6 | 4 | |||
| Asian | 16 | 7 | |||
| Pacific island | 7 | 17 | |||
| paternal ethnicity | 0.03 | yes | 0.88 | ||
| Caucasian | 8 | 3 | |||
| Asian | 14 | 9 | |||
| Pacific island | 7 | 16 | |||
a
Categorical variables were compared using χ2 test, whereas continuous variables were compared using t-test.
b
Yes if the factor is accounted for when building the classifier model.
c
Source of variation of the factor. It represents the contribution of the factor to the variability of the metabolomics data. It is the F-stats that were taken from a linear regression ANOVA model comprising maternal and paternal age, ethnicity, parity, and gravidity (Figure 1A).