Table 2.

The association between the AURKA rs2273535 T>A polymorphism and cancer risk in the meta-analysis.

Variables	No. of studies	Homozygous		Heterozygous		Recessive		Dominant		Allele
		AA vs. TT		AT vs. TT		AA vs. AT+TT		AT+AA vs. TT		A vs. T
		OR (95% CI)	Phet	OR (95% CI)	Phet	OR (95% CI)	Phet	OR (95% CI)	Phet	OR (95% CI)	Phet
All	36	1.17 (1.04-1.33)	0.000	1.02 (0.97-1.06)	0.096	1.15 (1.05-1.25)	0.000	1.06 (0.99-1.13)	0.003	1.07 (1.02-1.13)	0.000
Cancer type
Breast	13	1.28 (1.12-1.47)	0.089	1.02 (0.96-1.08)	0.098	1.17 (1.05-1.31)	0.008	1.10 (0.99-1.21)	0.042	1.09 (1.02-1.17)	0.006
Colorectal	3	1.13 (0.61-2.08)	0.038	1.05 (0.93-1.17)	0.258	1.15 (0.67-1.98)	0.012	1.01 (0.68-1.51)	0.074	1.05 (0.73-1.50)	0.003
Gastric	5	0.82 (0.60-1.13)	0.310	0.83 (0.63-1.09)	0.654	0.99 (0.79-1.24)	0.140	0.83 (0.64-1.07)	0.479	0.96 (0.80-1.14)	0.132
Others	15	1.15 (0.91-1.45)	0.000	1.02 (0.95-1.10)	0.130	1.14 (0.96-1.36)	0.000	1.05 (0.94-1.17)	0.013	1.08 (0.98-1.18)	0.000
Ethnicity
Caucasian	14	1.15 (0.95-1.39)	0.007	1.02 (0.96-1.08)	0.595	1.11 (0.96-1.28)	0.007	1.04 (0.98-1.10)	0.357	1.05 (0.99-1.11)	0.090
Asian	20	1.15 (0.98-1.34)	0.000	1.00 (0.93-1.07)	0.194	1.17 (1.05-1.32)	0.000	1.04 (0.94-1.15)	0.011	1.09 (1.01-1.18)	0.000
Strobe score
30-40	2	1.28 (0.92-1.78)	0.604	1.39 (0.99-1.95)	0.391	0.95 (0.83-1.08)	0.419	1.31 (0.95-1.82)	0.541	1.00 (0.89-1.12)	0.536
20-29	31	1.17 (1.02-1.34)	0.000	1.01 (0.95-1.07)	0.097	1.17 (1.06-1.29)	0.000	1.05 (0.97-1.12)	0.002	1.08 (1.02-1.14)	0.000
0-19	3	1.18 (0.90-1.53)	0.431	1.07 (0.90-1.28)	0.524	1.15 (0.92-1.45)	0.762	1.10 (0.93-1.30)	0.443	1.09 (0.97-1.23)	0.497
Design
HB	19	1.10 (0.91-1.33)	0.000	1.01 (0.95-1.08)	0.664	1.10 (0.95-1.27)	0.000	1.02 (0.94-1.11)	0.157	1.05 (0.97-1.13)	0.000
PB	16	1.25 (1.07-1.46)	0.002	1.02 (0.96-1.08)	0.009	1.19 (1.07-1.33)	0.001	1.10 (0.99-1.22)	0.001	1.10 (1.03-1.19)	0.000

OR, odd ratio; CI, confidence interval; Het, heterogeneity.