TABLE 2.
Biological processes that were the most affected for each conditiona
| Condition | Most affected biological process (score) |
|
|---|---|---|
| Upregulated | Downregulated | |
| BENZ | NA | Motility/flagellum (−1.56) |
| XID | Biotin metabolism (1.31) | Motility/flagellum (−2.52) |
| PHE | Biofilm (1.33) | Chemotaxis (−1.28) |
| GLUTA | Anaerobic growth (0.95) | Drug transport/response (−0.57) |
| H2O2 | Metabolism (0.62) | Aerobic growth (−1.15) |
| ETOH | Biofilm (1.46) | Aerobic growth (−1.33) |
| ISOP | Galactitol (1.86) | Chemotaxis (−2.80) |
| PERA | Biofilm (1.72) | Chemotaxis (−1.09) |
| POV | Biofilm (1.92) | Motility/flagellum (−1.81) |
| SOD | Biofilm (2.26) | Motility/flagellum (−0.98) |
| Long term | Biofilm (1.13) | Motility/flagellum (−1.27) |
| Long term | Glycerol (0.55) | Chemotaxis (−1.27) |
| BENZ30 | Drug transport/response (0.82) | Glycerol (−1.44) |
| PHE30 | Biotin metabolism (1.00) | Enterobactin (−1.92) |
| POV30 | Response to antibiotic (1.19) | Anaerobic growth (−1.34) |
| Short term | Chaperones (0.70) | Glycerol (−1.11) |
| Short term | Response to antibiotic (0.67) | Anaerobic growth (−1.05) |
a
The score corresponds to the average of the log2 fold change in expression for all the DEGs belonging to the corresponding pathway/biological process. The top up- and downregulated processes were also calculated for the average of all the conditions belonging to either short- or long-term exposure. NA, not applicable.