TABLE 4.
Relationship between yields of target aromatic compounds and Phe/Tyr
| Target compound | Avg yield (g/g glucose) ± SDa |
Enhancement (fold)b | |
|---|---|---|---|
| AR-G91 or its derivatives | M-PAR-120 or its derivatives | ||
| Phe | 0.14 ± 0.01 | 0.30 ± 0.00 | 2.1 |
| Tyr | 0.10 ± 0.01 | 0.26 ± 0.01 | 2.6 |
| Phenyllactic acid | 0.10 ± 0.01 (0.11 ± 0.02) | 0.17 ± 0.00 (0.22 ± 0.00) | 1.7 (2.0) |
| 4-Hydroxyphenyllactic acid | 0.11 ± 0.00 | 0.28 ± 0.00 | 2.5 |
| Tyramine | 0.07 ± 0.00 (0.07 ± 0.00) | 0.11 ± 0.04 (0.19 ± 0.01) | 1.6 (1.9) |
| Tyrosol | 0.14 ± 0.00 | 0.28 ± 0.01 | 2.0 |
Strains were cultivated in M9M2-0.5Y medium. The data are averages obtained from three independent cultures. The values in the parentheses are the total yields of the target aromatic compounds and Phe/Tyr.
The Phe yield obtained from M-PAR-120 or its derivative was divided by that obtained from AR-G91 or its derivative.