Table 4.

CVD Incidence Rates by Stage for Select Cancer Diagnoses and Comparison Cohort and Calculated Crude and Adjusted (Age, Sex, Race/Ethnicity, CVRFs, Overweight/Obesity, Smoking History) IRRs

Cancer Type and Stage	Cancer Survivors			Comparison Cohort			Crude IRR			Adjusted IRR
	No. With CVD	Person-Years	Incidence Rate*	No. With CVD	No. of Person-Years	Incidence Rate*	IRR	95% CI	P	IRR	95% CI	P
Breast
I	610	24,394.09	25.01	2,196	100,738.05	21.80	1.15	1.05 to 1.25	< .01	1.00	0.91 to 1.09	.97
II	518	19,823.11	26.13	2,196	100,738.05	21.80	1.20	1.09 to 1.32	< .01	1.21	1.10 to 1.34	< .01
III	102	3,927.28	25.97	2,196	100,738.05	21.80	1.19	0.98 to 1.45	.08	1.33	1.09 to 1.63	.01
IV	40	586.50	68.20	2,196	100,738.05	21.80	3.13	2.28 to 4.3	< .01	3.30	2.32 to 4.7	< .01
Kidney
I/II/III	141	4,133.15	34.11	284	10,454.74	27.16	1.26	1.03 to 1.54	.03	1.19	0.97 to 1.46	.1
IV	12	133.22	90.08	284	10,454.74	27.16	3.31	1.82 to 6.05	< .01	3.36	1.86 to 6.05	< .01
Lung and bronchus
I/II	117	1,954.08	59.87	478	12,728.58	37.55	1.59	1.3 to 1.95	< .01	1.39	1.10 to 1.75	.01
III/IV	94	1,268.1	74.13	478	12,728.58	37.55	1.97	1.58 to 2.47	< .01	2.01	1.56 to 2.6	< .01
Ovary
I	22	1,332.02	16.52	135	7,892.56	17.10	0.97	0.62 to 1.51	.88	1.11	0.72 to 1.71	.63
II/III/IV	51	1,455.13	35.05	135	7,892.56	17.10	2.05	1.48 to 2.83	< .01	1.78	1.26 to 2.5	< .01
Prostate
I/II	1,546	44,482.45	34.76	3,520	94,507.31	37.25	0.93	0.88 to 0.99	.02	0.89	0.84 to 0.95	< .01
III	118	4,277.95	27.58	3,520	94,507.31	37.25	0.74	0.62 to 0.89	< .01	0.79	0.66 to 0.95	.01
IV	57	1,306.32	43.63	3,520	94,507.31	37.25	1.17	0.89 to 1.53	.25	1.03	0.78 to 1.35	.86

Abbreviations: CVD, cardiovascular disease; CVRF, cardiovascular risk factors; IRR, incidence rate ratio.

^*Per 1,000 person-years.