Table 1.
Influence of Sympathetic Stimulation on Spontaneous and Evoked Synaptic Potentials in Young and Geriatric Mice
Mice | N Mice | N Fibers | MEPP Frequency | MEPP Amplitude | EPP Amplitude Prestimulation | EPP Amplitude Poststimulation | p Value (PRE vs POST) | QC Prestimulation | QC Poststimulation | p value (pre vs post) |
---|---|---|---|---|---|---|---|---|---|---|
Young | 6 | 26 (EPP) 43 (MEPP) | 7.822 (0.673) | 0.770 (0.013) | 30.8 (1.7) | 30.9 (1.7) | .968 | 39.3 (3.2) | 38.2 (3.3) | .816 |
Geriatric | 5 | 20 (EPP) 20 (MEPP) | 9.180§ (1.480) | 0.855§§ (0.032) | 22.5* (1.58) | 22.7** (1.68) | .933 | 29.2# (2.06) | 29.5## (2.2) | .967 |
Note: QC = Quantal content. SEM is between parentheses. The number of fibers ranged from 4 to 6 per mouse.
§MEPP frequency in young versus geriatric mice, p = .398. §§MEPP amplitude in young versus geriatric mice, p = .027. * Prestimulation EPP amplitude in young versus geriatric mice, p = .001; **Poststimulation EPP amplitude in geriatric versus young mice, p = .002; #Prestimulation QC in geriatric versus young mice, p = .014; ##Poststimulation QC in geriatric versus young mice, p = .087.