| 64 yr old male with history of smoking |
| Presented with RUL mass noted on CXR |
| Past medical history – high blood pressure, no CAD |
| WHO PS1 |
| PFT- FEV1 81% predicted; DLCO 86% predicted |
| CT thorax abdomen – right upper lobe tumor & enlarged station 4R (25.6 mm x 17.4 mm) |
| EBUS – positive 4R, 11R; negative 7, 4L, 10R |
| PET-CT - FDG right hilar adenopathy lymph node T2 N2 M0 |
| MR Brain – no metastases |
| Treatment – IMRT 66 Gy, concurrently with paclitaxel and carboplatin |
| 4 weeks post CRT |
| Decision to start with durvalumab 5 weeks after completion of CRT for a duration of 12 months |
| 2 months post CRT (on durvalumab) |
| PET-CT – Decreased avidity RUL mass and R hilar adenopathy |
| 8 months post CTRT (on durvalumab) |
| PET-CT- No FDG avidity in RUL mass, increased avidity R hilar adenopathy, no metastases |
| EBUS- positive 4R; negative 7, 4L |
| Referred for surgical evaluation |
|
PFT- FEV1 71% predicted; DLCO 74% predicted MRI Brain – no metastases Treatment - Robotic resection |